Development of Dermal Films Containing Miconazole Nitrate
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Bioadhesive Vaginal Suppositories Containing Miconazole Nitrate
Miconazole nitrate is an imidazole derivative antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. Over 90% of miconazole nitrate is reported to be bound to plasma proteins. In this study, miconazole nitrate was formulated into bioadhesive vaginal suppositories using different suppository bases such as fat...
متن کاملResearch studies on the quality of bio-mucoadhesive tablets containing miconazole nitrate.
Biomucoadhesive tablets are widely used to formulate topical antifungal drugs for treating acute oral candidiasis. The research focuses on the pharmaco-technological control of certain bio-mucoadhesive tablets containing miconazole nitrate, formulas developed and prepared by the authors based on the original formulas. The analyzed parameters were: macroscopic aspect, physical-chemical (pH) and ...
متن کاملDevelopment of Miconazole nitrate Thermosensitive Bioadhesive Vaignal Gel for Vaginal Candidiasis
Purpose: The aim of the present study was to formulate and evaluate miconazole nitrate containing thermosensitive bioadhesive gel for vaginal drug delivery to achieve a better therapeutic efficacy and patient compliance in the treatment for vaginal candidiasis. Method: Here miconazole nitrate (1%) was formulated as a vaginal gel using thermosensitive polymer, pluronic F127 (20%) along with bioa...
متن کاملDevelopment of Film Dosage Forms Containing Miconazole for the Treatment of Oral Candidiasis
Film dosage forms (FDs) containing miconazole (MCZ) for the treatment of oral candidiasis were prepared using water-soluble polysaccharides, and the dissolution profiles of MCZ from the FDs were investigated. In addition, the forms were modified by the addition of a surface active agent to accelerate the drug dissolution rate. Circular films incorporating MCZ were obtained using each polysaccha...
متن کاملNew Validated Stability Indicating Gradient Rp-hplc Method for the Assay &related Substances of Miconazole Nitrate and Assay of Benzoic Acid in Miconazole Nitrate 2.0% W/w Gel
An innovative, simple, economic, selective and sensitive of the stability indicating gradient reverse phase high performance liquid chromatography (RP-HPLC) method has been developed and validated for the analysis of assay of Miconazole nitrate and Benzoic acid and related substances of Miconazole nitrate in gel dosage form with better precision and accuracy. Miconazole nitrate & Benzioc acid a...
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ژورنال
عنوان ژورنال: Molecules
سال: 2018
ISSN: 1420-3049
DOI: 10.3390/molecules23071640